Abstract: The subject of this research is the reputation economy that represents a combination of social sciences studying distribution, exchange and consumption of goods and services as a result of formation of the positive reputation of economic agents within the global information space based on the system of “social proofs” affecting the development of cooperation ties, as well as providing them with the additional economic and social profit. The attention is focused on the formulation, explanation and substantial-functional characteristics of the conceptual-categorical apparatus, which reveals the distinct features of such terms as “economy”, “reputation economy” and “regional reputation economy”. Practice and empirical observations demonstrate that reputation activity of the economic agents forms a range of the prospects of their development. Therefore, reputation is highly important and receives widespread attention in the scientific research field. However, despite its popularization, the theory of reputation economy has yet not received due development and attention, which significantly limits the research paradigm based on studying the nonmaterial factors of production within the system of regional economic development or national economic systems overall. In this regard, an important mission in the development of economic science consists in devising of the concept and methodology of the theory of reputation economy applicable to the economic systems. This suggests the formulation and substantiation of a complex of theoretical considerations, as well as the development of the conceptual-categorical apparatus. This article is dedicated to partial solution of these questions.