Abstract: The subject of this research is the issues of medical social research on the correlation between the quality of life of a human with regards to health, and the professional health and professional longevity. The questions about the need of the expanded practical implementation of the medical social monitoring as an effective instrument of the personified (personalized) adaptive medicine is being examined in the course of this work. Based on the example of a flight crew with the digestive system illnesses, the authors demonstrate the practical importance of the medical social monitoring as an instrument for preservation and strengthening of health by the means of development and implementation of a complex of personified preventive care measures. The methodology of this research is based on the methods of medical sociology, aviation medicine, work hygiene, gastroenterology, qualimetry of life, and risks of health. The scientific novelty consists in the establishment of the importance of the life quality monitoring for the timely decision-making aimed at decreasing of the professionally diagnosed diseases of a flight crew. The article illustrates the applied possibilities of realization of such monitoring in order to preserve and strengthen the health of a flight crews, as well as increase their working efficiency and professional longevity.