Abstract: The life-time diagnostics and the diagnostics of the prescription of trauma is a topical and widely discussed problem. Macro- and microscopic description of characteristic features of tissue response serves as the basis for making a statement on the injuries received by a person during life-time and their prescription. However, the practice shows that the intervals of time when the trauma might have been caused which are established by expertise are not always sufficient for the judicial and investigative bodies, and sometimes a trauma itself does not get recognized. The modern laboratory (and, more specifically, immunohistochemical) examination methods currently have some potential for solving this problem. In spite of a rather short period of time of application of such method, their informative value is widely recognized. Unfortunately, due to a number of objective reasons, the immunohistochemical method are not widely applied by judicial medical experts. In order to prove the efficiency and necessity of introduction of high technology methods into the judicial medical practice the authors provide an example of using immunohistochemical method in a specific judicial medical expertise.