Abstract: The article examines the innovation center as an architectural object that creates conditions for research, cooperation between various economic entities and the production of knowledge-intensive products. The article subject is the design of innovation centers. The relevance of their consideration is due to the special attention of the state, the architectural community, and commercial enterprises. High quality of design solutions and symbolism of the architectural image are the basis for the innovation centers design, a competitive advantage in attracting and retaining highly skilled specialists. The study uses a graphic-analytical method and multifactor analysis of studying and systematizing the material (analysis of master plans, architectural drawings, engineering solutions). The contribution of the article consist in the identification and systematization of innovation centers architectural design solutions. The models of innovation centers design were made on urban, planning, and spatial characteristics of innovation centers. A computer program for data processing was used. The influence on the innovation centers design proceeds from organization structure, different types of ownership (university, government and commercial) and the location (city center, city district, suburbia, intercity territory). The total sample of the study consisted of 144 objects. It provides accurate result and the possibility of using the findings by professional architectural community.